In today’s fast-paced world, women often find themselves juggling numerous responsibilities, leading to stress, anxiety, and other mental health challenges. The demands of daily life can also impact sleep quality and overall brain function. However, there is an exciting new solution that has gained attention for its potential to positively impact mental health and overall well-being: psychobiotics. These next-generation probiotics have shown promise in addressing stress, depression, brain health, and sleep issues. 

What are Psychobiotics?

Psychobiotics for women's brain health

Psychobiotics are a novel class of probiotics that influence brain function and behavior through the gut-brain axis. The gut-brain axis refers to the bidirectional communication between the central nervous system and the gut microbiome, linking cognitive and emotional centers of the brain with intestinal functions. This axis plays a crucial role in influencing mood, cognition, and overall mental health. 

Psychobiotics produce and stimulate specific molecules that manipulate gut-brain signals via the gut-brain axis to help improve your psychological state. This means that they not only benefit gastrointestinal health but also (unlike conventional probiotics) have the potential to exert antidepressant and anxiolytic (anti-anxiety) effects, making them particularly relevant for women dealing with stress and mood-related challenges.

Benefits for Women’s Mental Health

The potential of psychobiotics for addressing neurological issues ranges from mild conditions like mood swings and anxiety to more intensive disorders like Alzheimer’s and Parkinson’s. They have been found to improve behavior, cognition, and physiological responses in stressed individuals. Psychobiotics have even shown promise in addressing neurological disorders such as autism spectrum disorder (ASD), with specific strains demonstrating positive effects on opposition/defiance behaviors and disruptive symptoms associated with ASD.

Improved Sleep

Psychobiotics offer a promising avenue for women struggling with sleep issues. Studies have indicated that the use of certain strains has led to significant improvements in sleep efficiency and patterns. This can be particularly beneficial for women looking to enhance the quality of their sleep and overall restfulness, especially in today’s society where sleep disturbances are common due to various stressors and lifestyle factors. By addressing sleep issues, psychobiotics offer a powerful new option for women to enhance their overall well-being and mental resilience, ultimately contributing to a healthier and more balanced lifestyle.

Reduced Anxiety and Depression

The potential of psychobiotics to address stress, anxiety and depression is particularly relevant for busy women seeking natural solutions to manage these challenges. Specific psychobiotic strains have been associated with reductions in stress, anxiety, and depression symptoms. For instance, Lactobacillus plantarum PS128 has been shown to reduce anxiety and depression-like behaviors, while also decreasing inflammation and corticosterone levels. Additionally, Lactobacillus helveticus NS8 has demonstrated effectiveness in reducing anxiety, depression, and cognitive dysfunction, along with increasing serotonin, norepinephrine, and brain-derived neurotrophic factor levels in the hippocampus. These examples are just a subset of positive outcomes and underscore the potential of psychobiotics in addressing stress, anxiety, and depression symptoms.

Cognitive Improvement and Brain Health

Psychobiotics have demonstrated positive effects cognitive function and mental clarity. Studies have shown that certain strains of psychobiotics can contribute to reducing brain fog and enhancing cognitive performance. For instance, specific psychobiotic strains (including Bifidobacterium longum 1714 and Lactobacillus rhamnosus JB-1) have been associated with improvements in memory, attention, and overall cognitive function in both animals and humans. Furthermore, the modulation of the gut-brain axis by psychobiotics has been linked to improved information processing, decision-making, and the ability to think clearly and effectively. Clearly psychobiotics show great potential in supporting cognitive health and optimizing mental acuity, both of which are priorities for creative and professional success.

Clinical Evidence and Research

Numerous clinical trials and studies have been conducted to explore the potential benefits of psychobiotics for mental health. The results have been encouraging, showing that consuming psychobiotics can be beneficial with minimal side effects. For example, experiments have shown that certain strains of psychobiotics (including Bifidobacterium longum 1714 strain) improve behavior, cognition, and physiological responses in stressed mice. Another strain (Lactobacillus rhamnosus (JB-1) has been found to reduce anxiety-induced corticosterone levels.

Practical Considerations for Women’s Wellness

Choosing and consuming supplements in isolation without an understanding of your underlying gut and brain health situation can be hit and miss, so consulting a functional medicine practitioner before integrating psychobiotics into your supplement plan is advisable. Ands while research is ongoing to fully understand their mechanisms, the potential benefits for women’s mental and emotional well-being are already well established.

How to Choose Psychobiotics

There are only a handful of commercially available psychobiotic probiotic products available from dispensaries today (which shows just how cutting edge this field truly is!) That’s a good thing in one way because you won’t have to get stressed and burn valuable brain cells over deciding which to choose!

One of our favorite psychobiotic supplement products is Zenbiome Cope from Microbiome Labs. It contains a unique strain of Bifidobacterium longum with an exopolysaccharide clinically shown to support a balanced mood, maintain optimal vitality, and help with occasional stress. 

Embracing the Potential of Psychobiotics

Zenbiome Cope Package

Psychobiotics are an exciting new probiotic option for enhancing mental wellness and gut-brain health, especially for women seeking natural and holistic approaches to managing stress, supporting mental health, and improving sleep. Embracing the potential of psychobiotics can help women prioritize their brain health and unlock their full creative and professional potential! 

Zenbiome COPE


Zenbiome™ COPE is designed to help clients better handle life’s occasional stressors. Zenbiome™ COPE pairs the well-researched psychobiotic 1714™ with other vital nutrients like B vitamins and herbal extracts to provide targeted support for coping with day-to-day, periodic stressors and mood changes.